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Article

From genes to trajectories: mapping genetic influences on Huntington's disease progression.

Bioinformatics (Oxford, England) - 28 Feb 2026

Dey Sanjoy, Sun Zhaonan, Warner John, Koski Eileen, Eyigoz Elif, Sathe Swati, Sampaio Cristina, Hu Jianying

Abstract excerpt

MOTIVATION: There are many diseases with established genetic factors, such as Huntington's disease (HD), that are characterized by variable rates of progression. However, beyond the contribution of the known genetic factors - in this case the Huntingtin (HTT) gene - the impact of the full human genome on the natural progression of such diseases throughout a patient's life remains largely unknown. The increased...

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Identifiers

PMID: 41692953
DOI: 10.1093/bioinformatics/btag072
PMCID: PMC13003314

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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