Article
Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials
2022-06-17
Abstract excerpt
<h4>Structured Abstract</h4> <h4>Background</h4> Neurodegenerative disease is increasing in prevalence and remains without disease-modifying therapies, and most trials of new drugs fail. Proposed solutions include aiming upstream: targeting molecular root causes of disease and testing therapies earlier, even at pre-symptomatic stages. We sought to understand what disease stages were eligible to enroll in neurodege...
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Identifiers and source
- Literature Corpus work
- 2c7e8753-997c-55c6-aa07-1336774c7583
- DOI
- 10.1101/2022.06.16.22276513