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Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation

1 Dec 2022

Abstract excerpt

Cancer-related deaths are mainly caused by metastatic spread of tumor cells from the primary lesion to distant sites via the blood circulation. Understanding the mechanisms of blood-borne tumor cell dissemination by the detection and molecular characterization of circulating tumor cells (CTCs) in the blood of patients with cancer has opened a new avenue in cancer research. Recent technical advances have enabled a...

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PMID: 36517082
DOI: 10.1136/jitc-2022-005615

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