Article
Four classic “de novo” genes all have plausible homologs and likely evolved from retro-duplicated or pseudogenic sequences
2023-05-30
Abstract excerpt
Despite being previously regarded as extremely unlikely, the idea that entirely novel protein-coding genes can emerge from non-coding sequences has gradually become accepted over the past two decades. Examples of “de novo origination”, resulting in lineage-specific “orphan” genes, lacking orthologs, are now produced every year. However, many are likely cases of duplicates that are difficult to recognize. Here, I r...
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Identifiers and source
- Literature Corpus work
- 694755b0-a5f9-591f-bd07-a43165267b2e
- DOI
- 10.1101/2023.05.28.542624