Article

Orphan and de novo Genes in Fungi and Animals: Identification, Origins and Functions

2025-06-03

Abstract excerpt

Genes that don't have identifiable homologs in other species have been an intriguing and interesting topic of research for many years. These so-called orphan genes were first studied in yeast and since then, they have been found in many other species. This has fostered a whole field of research aiming at tracing back their evolutionary origin and functional significance. Orphan genes represent an important part of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9985bd2f-cef1-5dc3-ac3a-768b353faeee
DOI: 10.32942/x2fw78

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Orphan and de novo Genes in Fungi and Animals: Identification, Origins and FunctionsDOI 10.32942/x2fw78Read

Orphan and hybrid two-component system proteins in health and diseaseSemantic proximity Read

Kelch-like proteins: Physiological functions and relationships with diseasesSemantic proximity Read

Synteny-based analyses indicate that sequence divergence is not the main source of orphan genesSemantic proximity Read

Getting your Pax straight: Pax proteins in development and diseaseSemantic proximity Read

Gene family innovation, conservation and loss on the animal stem lineage.Semantic proximity Read

Ensembl 2013.Semantic proximity Read

Four classic “de novo” genes all have plausible homologs and likely evolved from retro-duplicated or pseudogenic sequencesSemantic proximity Read

Mammalian Pax genes.Semantic proximity Read

Evolutionary and functional dynamics of chimeric pseudogenes (φgenes)Semantic proximity Read

Evolutionary developmental biology and genomics.Semantic proximity Read

Four classic “de novo” genes all have plausible homologs and likely evolved from retro-duplicated or pseudogenic sequencesSemantic proximity Read

Large-scale investigation of species-specific orphan genes in the human gut microbiome elucidates their evolutionary originsSemantic proximity Read