Article

A platform for efficient transgenesis in <i>Macrostomum lignano</i> , a flatworm model organism for stem cell research

2017-06-18

Abstract excerpt

<h4>ABSTRACT</h4> Regeneration-capable flatworms are informative research models to study the mechanisms of stem cell regulation, regeneration and tissue patterning. However, the lack of transgenesis methods significantly hampers their wider use. Here we report development of a transgenesis method for Macrostomum lignano , a basal flatworm with excellent regeneration capacity. We demonstrate that microinjection...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 69229200-44f6-5905-a1f6-ee2e0baa7029
DOI: 10.1101/151654

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A platform for efficient transgenesis in <i>Macrostomum lignano</i> , a flatworm model organism for stem cell researchDOI 10.1101/151654Read

Optimized protocols for RNA interference in <i>Macrostomum lignano</i>Semantic proximity Read

A novel flatworm-specific gene family implicated in reproduction in <i>Macrostomum lignano</i>Semantic proximity Read

Tim29 is required for stem cell activity during regeneration in the flatworm <i>Macrostomum lignano</i>Semantic proximity Read

Stable germline transgenesis using the <i>Minos</i> Tc1/ <i>mariner</i> element in the sea urchin, <i>Lytechinus pictus</i>Semantic proximity Read

One probe fits all: a highly customizable modular RNA <i>in situ</i> hybridization platform expanding the application of SABER DNA probesSemantic proximity Read

Heterologous reporter expression in the planarian <i>Schmidtea mediterranea</i> through somatic mRNA transfectionSemantic proximity Read

Mutational profile of the regenerative process and <i>de novo</i> genome assembly of the planarian <i>Schmidtea polychroa</i>Semantic proximity Read

A genome-wide MAGIC kit for recombinase-independent mosaic analysis in <i>Drosophila</i>Semantic proximity Read

Towards CRISPR/Cas9-based gene drive in the diamondback moth <i>Plutella xylostella</i>Semantic proximity Read

RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: methodology and dynamics.Semantic proximity Read

A universal vector concept for a direct genotyping of transgenic organisms and a systematic creation of homozygous lines.Semantic proximity Read

Genetic transformation of the frog-killing chytrid fungus <i>Batrachochytrium dendrobatidis</i>Semantic proximity Read