Article

Frequent recombination of pneumococcal capsule highlights future risks of emergence of novel serotypes

2017-01-04

Abstract excerpt

Capsular diversity of Streptococcus pneumoniae constitutes a major obstacle in eliminating the pneumococcal disease. Such diversity is genetically encoded by almost 100 variants of the capsule polysaccharide locus ( cps ). However, the evolutionary dynamics of the capsule – the target of the currently used vaccines – remains not fully understood. Here, using genetic data from 4,469 bacterial isolates, we found...

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Literature Corpus work: 68fa84e2-54f4-5c46-9f1c-09d6a8d07fc2
DOI: 10.1101/098335

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