Article

Benchmarking Twist Genotyping-by-Sequencing Against Whole-Genome Sequencing in Nuclear Families

2026-08-06

Abstract excerpt

Genome-wide genotyping is widely used in human genetics research, and targeted sequencing-based approaches such as the Twist Bioscience genome-wide SNP capture platform (GxS) have emerged as alternatives to conventional SNP arrays. Here, we evaluated GxS genotype calls from 555 individuals in 184 nuclear families against matched whole-genome sequencing (WGS) calls and compared platform performance with that of the...

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Literature Corpus work: 68f0ede3-37fb-589f-b864-71c33fc05544
DOI: 10.64898/2026.07.31.742127

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