Article

16GT: a fast and sensitive variant caller using a 16-genotype probabilistic model

2017-02-24

Abstract excerpt

<h4>Summary</h4> 16GT is a variant caller for Illumina WGS and WES germline data. It uses a new 16-genotype probabilistic model to unify SNP and indel calling in a single variant calling algorithm. In benchmark comparisons with five other widely used variant callers on a modern 36-core server, 16GT ran faster and demonstrated improved sensitivity in calling SNPs, and it provided comparable sensitivity and accurac...

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Literature Corpus work: 03308214-83fc-57a7-a753-bd4231330d9d
DOI: 10.1101/111393

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