Article
Legacy Effects of Early β-Adrenergic Stimulation Program Adipose Plasticity and Confer Metabolic Resilience in Obesity
2026-06-29
Abstract excerpt
Pathologic white adipose tissue (WAT) remodeling, characterized by fibrosis, inflammation, and adipocyte dysfunction, is a hallmark and driver of metabolic disease in obesity 1 . Here, we show that legacy effects of early physiological or pharmacological interventions driving adaptive adipose remodeling can mitigate maladaptive WAT remodeling and metabolic dysfunction when developing obesity later in life. Cold e...
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Identifiers and source
- Literature Corpus work
- 68d50ed8-9a5b-53ff-a68b-4c948f3a79b9
- DOI
- 10.64898/2026.06.23.734002