Article

Cold exposure drives weight gain and adiposity following chronic suppression of brown adipose tissue

2019-10-02

Abstract excerpt

Therapeutic activation of thermogenic brown adipose tissue (BAT) may be feasible to prevent, or treat, cardiometabolic disease. However, rodents are commonly housed below thermoneutrality (∼20°C) which can modulate their metabolism and physiology including the hyperactivation of brown (BAT) and beige white adipose tissue. We housed animals at thermoneutrality from weaning to chronically supress BAT, mimic human ph...

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Literature Corpus work: 4e16635c-0ac9-5f88-a715-11e11935963a
DOI: 10.1101/789289

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