Article
Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype.
International journal of obesity (2005) - 1 Mar 2017
Flachs P, Adamcova K, Zouhar P, Marques C, Janovska P, Viegas I, Jones J G, Bardova K, Svobodova M, Hansikova J, Kuda O, Rossmeisl M, Liisberg U, Borkowska A G, Kristiansen K, Madsen L, Kopecky J
Abstract excerpt
BACKGROUND/OBJECTIVE: Futile substrate cycling based on lipolytic release of fatty acids (FA) from intracellular triacylglycerols (TAG) and their re-esterification (TAG/FA cycling), as well as de novo FA synthesis (de novo lipogenesis (DNL)), represent the core energy-consuming biochemical activities of white adipose tissue (WAT). We aimed to characterize their roles in cold-induced thermogenesis and energy...
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