Article

Ginsenoside Rg1 alleviates Aβ deposition and neuronal damage by inhibiting NLRP1 inflammasome activation in APP/PS1 mice

2020-08-02

Abstract excerpt

<h4>Background: </h4> Oxidative stress and neuroinflammation play important roles in the whole pathogenesis of Alzheimer's disease (AD). NADPH oxidase 2 (NOX2) is an important enzyme that is responsible for ROS generation in many neurodegenerative diseases. The nucleotide-binding oligomerization domain (NOD)-like receptor protein 1 (NLRP1) inflammasome is responsible for the formation of pro-inflammatory molecules...

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Literature Corpus work: 68b94c8c-ae70-555b-9a44-e6974e88bf73
DOI: 10.21203/rs.3.rs-49467/v1

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