Article

Tristetraprolin/ZFP36 regulates the turnover of autoimmune-associated HLA-DQ mRNAs

2018-06-06

Abstract excerpt

We have previously demonstrated that the expression of HLA class II genes is regulated by the binding of a ribonucleoprotein complex that affects the mRNA processing. We identified protein components of a complex binding transcripts encoding the HLA-DR molecule. Here we investigate whether the same RNA binding proteins interact with 3’UTR of mRNAs encoding the HLA-DQ isotype. Specifically, we focused on the HLA-DQ...

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Literature Corpus work: 689f07f6-eda1-5177-86fc-234f136c7911
DOI: 10.1101/337907

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