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Article

Multiple functions of tristetraprolin/TIS11 RNA-binding proteins in the regulation of mRNA biogenesis and degradation.

Cellular and molecular life sciences : CMLS - 1 Jun 2013

Ciais Delphine, Cherradi Nadia, Feige Jean-Jacques

Abstract excerpt

Members of the tristetraprolin (TTP/TIS11) family are important RNA-binding proteins initially characterized as mediators of mRNA degradation. They act via their interaction with AU-rich elements present in the 3'UTR of regulated transcripts. However, it is progressively appearing that the different steps of mRNA processing and fate including transcription, splicing, polyadenylation, translation, and degradation...

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Identifiers

PMID: 22968342
DOI: 10.1007/s00018-012-1150-y
PMCID: PMC11113850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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