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Mechanism, and treatment of anti-CV2/CRMP5 autoimmune pain

2024-05-07

Abstract excerpt

Paraneoplastic neurological syndromes arise from autoimmune reactions against nervous system antigens due to a maladaptive immune response to a peripheral cancer. Patients with small cell lung carcinoma or malignant thymoma can develop an autoimmune response against the CV2/collapsin response mediator protein 5 (CRMP5) antigen. For reasons that are not understood, approximately 80% of patients experience painful n...

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Identifiers and source

Literature Corpus work
688bf81c-77e8-5149-ad94-8922d5c6909a
DOI
10.1101/2024.05.04.592533
Open publication

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Mechanism, and treatment of anti-CV2/CRMP5 autoimmune painDOI 10.1101/2024.05.04.592533
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