Article

Restricted sequence variation in <i>Streptococcus pyogenes</i> penicillin binding proteins

2020-01-25

Abstract excerpt

A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutations in the Penicillin Binding Protein PBP2x. To determine whether this is an isolated case or reflects a broader prevalence of mutations that might confer reduced β-lactam susceptibility, we investigated the relative frequency of penicillin binding protein (PBP) sequence variation within a global database of 9,667...

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Identifiers and source

Literature Corpus work: 687c629c-87f2-5909-b519-c3fff3925dc6
DOI: 10.1101/2020.01.24.919308

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