Article

UMITIC: An unsupervised framework for the joint characterization of cellular phenotypes and spatial neighborhoods in multiplex and hyperplex immunofluorescence imaging data

2026-06-01

Abstract excerpt

Multiplexed imaging technologies enable the simultaneous measurement of dozens of protein markers while preserving context, providing a high-resolution view of tissue organization schemes. However, extracting meaningful insights from these high-dimensional datasets—particularly in hyperplex settings (>20 markers)—remains a major computational challenge, especially in the absence of annotated data. Here, we present...

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Literature Corpus work: eb490926-759c-5d43-8c29-2e0219dc3f6d
DOI: 10.64898/2026.05.29.728633

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