Article

Detection of Spatially Aberrant Cells in Spatial Transcriptomics Data by Conformal Prediction

2026-08-15

Abstract excerpt

The hexagonal organization of epithelial cells represents a fundamental feature of normal tissue architecture, reflecting the precise spatial coordination that underlies healthy biological structure. Disruptions to this organization-manifesting as spatially aberrant spots with abnormal gene expression and misplaced positioning-are closely associated with disease initiation and progression. Here, we introduce SPADE...

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Literature Corpus work: c3176ab8-b6ac-5d63-a629-84fc7a663c09
DOI: 10.64898/2026.08.12.744448

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