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PfAMA1-expressing chimeric rodent malaria parasites provide an in vivo platform for evaluating multistage interventions against malaria

2026-08-30

Abstract excerpt

Apical membrane antigen 1 (AMA1) is expressed in the merozoite and sporozoite infectious stages of the malaria parasite, and upon secretion plays essential roles during host cell invasion. AMA1 is a leading candidate for vaccine development, although specific antibodies frequently fail to inhibit the growth of field-isolated Plasmodium falciparum malaria parasites, likely due to the high diversity of polymorphisms...

Identifiers and source

Literature Corpus work
67e3c939-e5d6-5c7b-9432-f24dcfb69cd0
DOI
10.64898/2026.08.28.747760
Open publication

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PfAMA1-expressing chimeric rodent malaria parasites provide an in vivo platform for evaluating multistage interventions against malariaDOI 10.64898/2026.08.28.747760
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