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<i>Babesia divergens</i> and <i>Neospora caninum</i> apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion

20 Nov 2012

Abstract excerpt

Host cell invasion by the obligate intracellular apicomplexan parasites, including Plasmodium (malaria) and Toxoplasma (toxoplasmosis), requires a step-wise mechanism unique among known host-pathogen interactions. A key step is the formation of the moving junction (MJ) complex, a circumferential constriction between the apical tip of the parasite and the host cell membrane that traverses in a posterior direction...

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PMID: 23169033
DOI: 10.1002/pro.2193

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