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Epigenetic control of microglial developmental milestones from proliferative progenitors to efficient phagocytes

2025-11-04

Abstract excerpt

Early immune perturbations increase the risk of neurodegenerative and neurodevelopmental disorders, yet the mechanisms underlying the maturation of microglia, the resident immune cells of the brain parenchyma, remain poorly defined. Specifically, how proliferation, morphological differentiation, and phagocytosis are coordinated among microglia progenitors as they colonize the embryonic brain remains unclear. Here,...

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Literature Corpus work
67d8c0bf-7073-51cb-a585-669af448702a
DOI
10.1101/2025.11.03.685577
Open publication

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Epigenetic control of microglial developmental milestones from proliferative progenitors to efficient phagocytesDOI 10.1101/2025.11.03.685577
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