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Article

Early-childhood inflammation blunts the transcriptional maturation of cerebellar neurons

2022-07-26

Abstract excerpt

Inflammation early in life is a clinically established risk factor for autism spectrum disorders and schizophrenia, yet the impact of inflammation on human brain development is poorly understood. The cerebellum undergoes protracted postnatal maturation, making it especially susceptible to perturbations contributing to risk of neurodevelopmental disorders. Here, using single-cell genomics, we characterize the postn...

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Literature Corpus work
f1194572-7ff9-5258-a990-04ca677c032a
DOI
10.1101/2022.07.26.501598
Open publication

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Early-childhood inflammation blunts the transcriptional maturation of cerebellar neuronsDOI 10.1101/2022.07.26.501598
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