Article

Choice of Isolation method has a significant impact on average murine Telomere Length estimates

2022-08-24

Abstract excerpt

<h4>Background: </h4> Telomere Length (TL) and integrity is significantly associated with age-related disease, multiple genetic and environmental factors. We observe mouse genomic DNA (gDNA) isolation methods have a significant impact on average TL estimates. The canonical qPCR method does not measure TL directly but via the ratio of telomere repeats to a single copy gene (SCG) generating an TS ratio. We use an mm...

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Literature Corpus work: 67bd1671-29fe-5032-b3bd-4aafeb9bf32e
DOI: 10.21203/rs.3.rs-1870657/v1

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