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Article

Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood

4 Dec 2015

Abstract excerpt

Telomeres are located at chromosome ends and their length (TL) has been associated with aging and human diseases such as cancer. Whole blood DNA is frequently used for TL measurements but the influence of preanalytical conditions and DNA isolation methods on TL quantification has not been thoroughly investigated. To evaluate potential preanalytical as well as methodological bias on TL, anonymized leftover...

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PMID: 26636575
DOI: 10.1371/journal.pone.0143889

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