Article
A Synthetic Single-Stranded Dual-Template Oligonucleotide as a Reference Standard for Monochrome Multiplex qPCR Measurements of Average Telomere Length
2020-06-25
Abstract excerpt
<h4>ABSTRACT</h4> Quantitative PCR is frequently used to measure average telomere length (TL) relative to the TL of a reference DNA sample of the investigator’s choosing. This makes comparisons of TLs across studies and laboratories difficult. Here we demonstrate that a single synthetic single-stranded dual-template oligonucleotide (DTO) containing both a telomere repeat sequence (T) and a segment of the human be...
Topics
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- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Chromosomal and Genetic Variations
- Cytomegalovirus and herpesvirus research
- Microplastics and Plastic Pollution
- Molecular Biology Techniques and Applications
- Single-cell and spatial transcriptomics
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- 7f96b044-938c-56e6-a67a-f2a450ee1ece
- DOI
- 10.1101/2020.06.24.169797
