Article

14-3-3η Induces a Multidrug-Resistant Phenotype in Rheumatoid Arthritis via p53 Dysregulation: Insights from AIA Models

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>Rheumatoid arthritis (RA) is a chronic autoimmune condition complicated by drug resistance issues, significantly challenging its treatment. The protein 14-3-3η has been noted for its association with drug resistance in various cancers, and while it is particularly expressed at high levels in RA patients, its role in the disease's pathogenesis is not well understood. This study explores...

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Literature Corpus work: 6796124e-f0ac-5634-8b4e-d54045b2deba
DOI: 10.21203/rs.3.rs-6528370/v1

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