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Article

Potential mechanisms of action of celastrol against rheumatoid arthritis: transcriptomic and proteomic analysis

2020-03-09

Abstract excerpt

<title>Abstract</title> <p>Background: The natural triterpene celastrol exhibits potential anti-inflammatory activity in inflammatory diseases such as rheumatoid arthritis (RA). <h4>Methods:</h4> Here we explored through what proteins and processes celastrol may act in activated fibroblast-like synoviocytes (FLS) from RA patients. Differential expression of genes and proteins after celastrol treatment of FLS was...

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Literature Corpus work
90bced5a-362b-5e75-911c-e66f805fe60d
DOI
10.21203/rs.3.rs-16420/v1
Open publication

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Potential mechanisms of action of celastrol against rheumatoid arthritis: transcriptomic and proteomic analysisDOI 10.21203/rs.3.rs-16420/v1
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