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Article

Potential mechanisms of action of celastrol against rheumatoid arthritis: transcriptomic and proteomic analysis

2020-05-14

Abstract excerpt

<h4>Background</h4> The natural triterpene celastrol exhibits potential anti-inflammatory activity in inflammatory diseases such as rheumatoid arthritis (RA). <h4>Methods</h4> Here we explored through what proteins and processes celastrol may act in activated fibroblast-like synoviocytes (FLS) from RA patients. Differential expression of genes and proteins after celastrol treatment of FLS was examined using RNA...

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Literature Corpus work
21e47aed-8551-5c2f-901b-300e73025ed6
DOI
10.1101/2020.05.14.095737
Open publication

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Potential mechanisms of action of celastrol against rheumatoid arthritis: transcriptomic and proteomic analysisDOI 10.1101/2020.05.14.095737
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