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Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis

11 Apr 2017

Abstract excerpt

OBJECTIVE: Sirtuins (SIRTs) play a prominent role in metabolism, apoptosis, aging, inflammation, and epigenetics. Inflammation, apoptosis, and epigenetics are pathogenic issues in rheumatoid arthritis (RA). This study aimed to evaluate SIRT2 and SIRT3 mRNA expressions in patients with RA. MATERIAL AND METHODS: Fifty-four patients with RA and 26 healthy controls were enrolled. Disease activity was determined using...

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PMID: 28638677
DOI: 10.5152/eurjrheum.2017.16056

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