Article

A Novel <i>Ex Vivo</i> Peritoneal Model to Investigate Mechanisms of Peritoneal Metastasis in Gastric Adenocarcinoma

2021-11-17

Abstract excerpt

<h4>ABSTRACT</h4> Peritoneal metastases (PM) portend limited survival in patients with Gastric Adenocarcinoma (GCa), and strategies to prevent and/or more effectively treat PM are needed. Existing models are limited in recapitulating key elements of the peritoneal metastatic cascade. To explore the underlying cellular and molecular mechanisms of PM, we have developed an ex vivo human peritoneal explant model. Fr...

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Literature Corpus work: 67357f41-30be-5216-92fd-92d3ea7ee75b
DOI: 10.1101/2021.11.15.468687

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