Article

Hypoxia-Autophagy Axis Induces VEGFA by Peritoneal Mesothelial Cells to Promote Gastric Cancer Peritoneal Metastasis Through an Integrin α5-Fibronectin Pathway

2020-08-02

Abstract excerpt

<h4>Background: </h4> Peritoneal metastasis (PM) is an important pathological process in the progression of gastric cancer (GC). The metastatic potential of tumor and stromal cells is governed by hypoxia, which is a key molecular feature of the tumor microenvironment. Mesothelial cells also participate in this complex and dynamic process. However, the molecular mechanisms underlying the hypoxia-driven mesothelial-...

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Literature Corpus work: 9bc00df6-4a12-5352-be0f-86f3272447d1
DOI: 10.21203/rs.3.rs-49284/v1

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