Article

TGF-β1 activates neutrophil signaling and gene expression but not migration

2023-05-27

Abstract excerpt

Tumor-associated neutrophils are found in many types of cancer and are often reported to contribute to negative outcomes. The presence of transforming growth factor-beta (TGF-β) in the tumor microenvironment reportedly contributes to the skewing of neutrophils to a more pro-tumor phenotype. The effects of TGF-β on neutrophil signaling and migration are, however, unclear. We sought to characterize TGF-β signaling i...

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Literature Corpus work: 670e6409-dca0-5ef6-8b1d-78756636abd1
DOI: 10.1101/2023.05.26.542468

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