Article
Neutrophils in cancer: dual roles through intercellular interactions.
Oncogene - 1 Apr 2024
Yu Xinyu, Li Changhui, Wang Zijin, Xu Yaping, Shao Shiqun, Shao Fangwei, Wang Hua, Liu Jian
Abstract excerpt
Neutrophils, the most abundant immune cells in human blood, play crucial and diverse roles in tumor development. In the tumor microenvironment (TME), cancer cells regulate the recruitment and behaviors of neutrophils, transforming some of them into a pro-tumor phenotype. Pro-tumor neutrophils interact with cancer cells in various ways to promote cancer initiation, growth, and metastasis, while anti-tumor...
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