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Article

Antimicrobial activity of the recombinant peptide Melittin-Thanatin with three glycine to tryptophan mutations.

Preparative biochemistry & biotechnology - 1 Jan 2023

Liu Yong, Zhang Xiuping, Meng Chunyan, Ji Shengyue, Guo Kangkang

Abstract excerpt

The antimicrobial peptide was considered an important target for developing novel antibacterial drugs. However, the unstable biological activity and the low antibacterial activity are challenges for the application of recombinant proteins. In this study, the fusion peptide of Melittin-Thanatin (MT) was designed and produced, and its derivative sequence (MT-W) was obtained by replacing three glycines (Gly, G) with...

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PMID: 36508334
DOI: 10.1080/10826068.2022.2151016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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