Article

The Role of Ryanodine Receptor 2 in Drug-Associated Learning

2023-10-05

Abstract excerpt

Type-2 ryanodine receptor (RyR2) ion channels facilitate the release of Ca 2+ from stores and serve an important function in neuroplasticity. The role for RyR2 in hippocampal-dependent learning and memory is well established and chronic hyperphosphorylation of RyR2 (RyR2P) is associated with pathological calcium leakage and cognitive disorders, including Alzheimer’s disease. By comparison, little is known about t...

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Literature Corpus work: 66c88004-2187-5f00-bc3d-c5caaa3d2396
DOI: 10.1101/2023.10.03.560743

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