Article

Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

2023-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of β-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by which oncogenic β-catenin affects immune surveillance remain unclear. Herein, we highlighted the involvement of β-catenin in the regulation of the exosomal pathway a...

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Literature Corpus work: 66a6debb-3425-5026-ba83-d83ab633e453
DOI: 10.1101/2023.10.24.563805

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