Article

No replicable morphometry variations and limited morphometry-phenotype associations for cortical neuroimaging in irritable bowel syndrome

2025-12-08

Abstract excerpt

<title>Abstract</title> <p>Irritable bowel syndrome (IBS) is a common disorder of gut-brain interaction that has sparked interest in neural markers. Yet, previous neuroimaging findings remain inconsistent and often fail to replicate, likely due to small sample sizes that overestimate effects and overlook patient heterogeneity. Using normative modeling to quantify cortical deviations from MRI in IBS and matched co...

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Literature Corpus work: 66875164-f7a7-5dd7-ae07-1b92cb489660
DOI: 10.21203/rs.3.rs-8232200/v1

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