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Irritable Bowel Syndrome Is Associated With Brain Health by Neuroimaging, Behavioral, Biochemical, and Genetic Analyses.

Biological psychiatry - 15 Jun 2024

Li Zeyu, Ma Qing, Deng Yueting, Rolls Edmund T, Shen Chun, Li Yuzhu, Zhang Wei, Xiang Shitong, Langley Christelle, Sahakian Barbara J, Robbins Trevor W, Yu Jin-Tai, Feng Jianfeng, Cheng Wei

Abstract excerpt

BACKGROUND: Irritable bowel syndrome (IBS) interacts with psychopathology in a complex way; however, little is known about the underlying brain, biochemical, and genetic mechanisms. METHODS: To clarify the phenotypic and genetic associations between IBS and brain health, we performed a comprehensive retrospective cohort study on a large population. Our study included 171,104 participants from the UK Biobank who...

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PMID: 38199582
DOI: 10.1016/j.biopsych.2023.12.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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