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Article

Genetic basis to structural grey matter associations with chronic pain.

Brain : a journal of neurology - 31 Dec 2021

Farrell Scott F, Campos Adrián I, Kho Pik-Fang, de Zoete Rutger M J, Sterling Michele, Rentería Miguel E, Ngo Trung Thanh, Cuéllar-Partida Gabriel

Abstract excerpt

Structural neuroimaging studies of individuals with chronic pain conditions have often observed decreased regional grey matter at a phenotypic level. However, it is not known if this association can be attributed to genetic factors. Here we employed a novel integrative data-driven and hypothesis-testing approach to determine whether there is a genetic basis to grey matter morphology differences in chronic pain....

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PMID: 34907416
DOI: 10.1093/brain/awab334

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