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Article

Gene, environment, and brain-gut interactions in irritable bowel syndrome.

Journal of gastroenterology and hepatology - 1 Apr 2011

Fukudo Shin, Kanazawa Motoyori

Abstract excerpt

The genetic predisposition and influence of environment may underlie in the pathogenesis and/or pathophysiology of irritable bowel syndrome (IBS). This phenomenon, gene x environment interaction together with brain-gut interactions is emerging area to be clarified in IBS research. Earlier studies focused on candidate genes of neurotransmitters, cytokines, and growth factors. Among them, some studies but not all...

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Identifiers

PMID: 21443722
DOI: 10.1111/j.1440-1746.2011.06631.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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