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Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome

28 Apr 2017

Abstract excerpt

BACKGROUND: Preclinical and clinical evidence supports the concept of bidirectional brain-gut microbiome interactions. We aimed to determine if subgroups of irritable bowel syndrome (IBS) subjects can be identified based on differences in gut microbial composition, and if there are correlations between gut microbial measures and structural brain signatures in IBS. METHODS: Behavioral measures, stool samples, and...

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PMID: 28457228
DOI: 10.1186/s40168-017-0260-z

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