Back to search

Article

Evaluation of a DNA methylation-based measure of chronic inflammation in two generations of adults in metropolitan Cebu, Philippines

2025-03-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Proxy measures of chronic inflammation derived from DNA methylation (DNAm) data have emerged as promising predictors of cardiometabolic disease risk in high income countries. This study investigates the performance of a recently validated DNAm-based measure of C-reactive protein (DNAm-CRP) in two generations of adults in the Philippines to evaluate its utility in lower and mid...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
666b2cc2-72aa-5b37-8ab2-abe549f2e0a5
DOI
10.1101/2025.03.25.25324477
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Evaluation of a DNA methylation-based measure of chronic inflammation in two generations of adults in metropolitan Cebu, PhilippinesDOI 10.1101/2025.03.25.25324477
Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohortsSemantic proximity
A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long‐term inflammatory exposure: A Canadian Longitudinal Study on Aging analysisSemantic proximity
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.Semantic proximity
Circulating levels of inflammatory markers and DNA methylation, an analysis of repeated samples from a population based cohortSemantic proximity
A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (InfLaMeS): results from the Health and Retirement StudySemantic proximity
Analysis of C-reactive protein omics-measures associates methylation risk score with sleep health and related health outcomesSemantic proximity
A novel framework to build saliva-based DNA methylation biomarkers: quantifying systemic chronic inflammation as a case studySemantic proximity
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseasesSemantic proximity
Genetic analysis of over half a million people characterises C-reactive protein loci.Semantic proximity
How Routinely Assessed Biomarkers Can Be Utilized To Identify Individuals With A High Disease Burden: A Bioinformatics Approach Towards Predictive, Preventive And Personalised (3P) MedicineSemantic proximity
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.Semantic proximity
Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthoodSemantic proximity
Select a neighboring publication to make it the new centre.