Article
A novel framework to build saliva-based DNA methylation biomarkers: quantifying systemic chronic inflammation as a case study
2023-12-23
Abstract excerpt
Accessible and non-invasive biomarkers that measure human ageing processes and the risk of developing age-related disease are paramount in preventative healthcare. In this study, we describe a novel framework to train saliva-based DNA methylation (DNAm) biomarkers that are reproducible and biologically interpretable. By leveraging a reliability dataset with replicates across tissues, we demonstrate that it is poss...
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Identifiers and source
- Literature Corpus work
- 4ee69db7-57c8-5e87-989c-3d7632e56f18
- DOI
- 10.1101/2023.12.21.572866