Article

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

2021-08-10

Abstract excerpt

<title>Abstract</title> <p>We performed a trans-ethnic Epigenome Wide Association study on 22,774 individuals to describe the DNA methylation signature of chronic low-grade inflammation as measured by C-Reactive protein (CRP). We found 1,511 independent differentially methylated loci associated with CRP. These CpG sites showed correlation structures across chromosomes, and were primarily situated in euchromatin,...

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Literature Corpus work: fc55f1b6-1c63-5e19-96ea-fe8067c31f8d
DOI: 10.21203/rs.3.rs-688986/v1

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