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Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood

3 Jul 2017

Abstract excerpt

Chronic inflammation contributes to a wide range of human diseases, and environments in infancy and childhood are important determinants of inflammatory phenotypes. The underlying biological mechanisms connecting early environments with the regulation of inflammation in adulthood are not known, but epigenetic processes are plausible candidates. We tested the hypothesis that patterns of DNA methylation (DNAm) in...

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PMID: 28673994
DOI: 10.1073/pnas.1620661114

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