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Article

Molecular diagnostics identifies risks for graft dysfunction despite borderline histologic changes.

Kidney international - 1 Oct 2015

Hrubá Petra, Brabcová Irena, Gueler Faikah, Krejčík Zdeněk, Stránecký Viktor, Svobodová Eva, Malušková Jana, Gwinner Wilfried, Honsová Eva, Lodererová Alena, Oberbauer Rainer, Zachoval Roman, Viklický Ondřej

Abstract excerpt

The significance of borderline changes in kidney allograft biopsies is widely debated. To help resolve this, we studied differences in intrarenal gene expression patterns between early clinical and 3-month protocol biopsies, all of which had borderline histologic changes. The gene expression profiles in training set of patients by microarray analysis and data were validated in a larger cohort using RT-qPCR. There...

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PMID: 26176825
DOI: 10.1038/ki.2015.211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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