Article
Lactylation: A Novel Post-Translational Modification with Clinical Implications in CNS Diseases
2024-07-19
Abstract excerpt
Lactate, an important metabolic product, provides energy to neural cells during energy depletion or high demand and acts as a signaling molecule in the central nervous system. Recent studies revealed that lactate-mediated protein lactylation regulates gene transcription and influences cell fate, metabolic processes, inflammation, and immune responses. This review comprehensively examines the regulatory roles and m...
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Identifiers and source
- Literature Corpus work
- 664e3552-b18e-5a1d-8a3b-ccf83d818296
- DOI
- 10.20944/preprints202407.1493.v1