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Article

Mapping the Analytical Landscape of Gene-Diet Interactions in Epidemiology: From Classical Models to Causal and Multi-Omics Frameworks.

Nutrients - 10 Mar 2026

Maugeri Andrea

Abstract excerpt

Diet is a major, modifiable determinant of cardiometabolic, cancer, and inflammatory disease risk, yet individuals frequently exhibit substantial heterogeneity in metabolic and clinical responses to similar dietary exposures. Genetic susceptibility and its interplay with diet plausibly contribute to this variability, motivating gene-diet (G×D) interaction research and the broader ambition of precision nutrition....

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PMID: 41901055
DOI: 10.3390/nu18060880
PMCID: PMC13029346

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