Article
Replication fork collapse at a protein-DNA roadblock leads to fork reversal, promoted by the RecQ helicase
2018-05-14
Abstract excerpt
There are numerous impediments that DNA replication can encounter while copying a genome, including the many proteins that bind DNA. Collapse of the replication fork at a protein roadblock must be dealt with to enable replication to eventually restart; failure to do so efficiently leads to mutation or cell death. Several prospective models have been proposed that process a stalled or collapsed replication fork. Th...
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Identifiers and source
- Literature Corpus work
- 662162c0-6d5d-5df3-ab4c-cb9265d03046
- DOI
- 10.1101/321869